High schooler Greg, who spends most of his time making parodies of classic movies with his co-worker Earl, finds his outlook forever altered after befriending a classmate who has just been diagnosed with cancer.
In the midst of veteran con man Nicky's latest scheme, a woman from his past - now an accomplished femme fatale - shows up and throws his plans for a loop.
After young Riley is uprooted from her Midwest life and moved to San Francisco, her emotions - Joy, Fear, Anger, Disgust and Sadness - conflict on how best to navigate a new city, house, and school.
Follows Shane and Oliver who help a young boy fighting leukemia reunite with his long-lost friend while preparing for their wedding. Also, Rita and Norman deal with the challenges of trying to start a family.
Lucy and Jane have been best friends their entire lives. Only when Lucy embarks on a personal journey, will she face a test of her friendship, and her sense of self, on a path she may not be entirely ready to take.
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